Celestamine tablet is a steroid drug used to treat allergic conditions, respiratory disorders, and urticaria (skin diseases).
It is a corticosteroid medicine produced from the combination of betamethasone and dexchlorpheniramine.
Several studies on the efficacy of the drug showed that it is effective in treating
- Nasal polyposis
- Allergic rhinitis
- Sinusitis infection
- Inflammatory disorders
- Respiratory problems and others.
Celestamine is produced using steroids and antihistamine drugs, this results in their anti-inflammatory and anti-allergic properties.
They manufactured the drug using
- Betamethasone: 250 mcg/tablet, and
- Dexchlorpheniramine maleate: 2 mg/tablet.
It comes in different forms such as
- Tablets or pills
- Syrup, etc.
Uses of a celestamine ns (Betadexin)
Celestamine is used to treat, prevent and control many complications such as
- Skin inflammation and dermatitis
- Blood diseases
- Allergic diseases such as asthma, angioedema.
- Ataxia telangiectasia
- Breathing difficulties
- Phimosis and other complications.
Celestamine dosage for babies and adults
The usual dose of this drug is commonly based on the severity of the ailment and is gradually reduced to the lowest minimum as the patient recovers.
- For children under the age of 2- 6 years, a dose of 1/4 tablets or 1/2 tablespoons is recommended 3 times a day.
- Children of 6- 12 years: 1/2 tablets or 1/2 tablespoons of syrup, 3 times a day.
- Those older than 12 years: 1 or 2 tablets or tablespoons, 4 times a day.
- Adults, 2- 6 tablets a day.
However, always follow your doctor’s instructions and recommendations to avoid an overdose or underdose of the drug.
Common side effects of celestamine medicine
Abusive use of a celestamine drug comes with some side effects which may be severe or mild,
Below are some side effects.
Betamethasone and high blood pressure
Betamethasone is usually administered to pregnant women during antenatal to prevent neonatal respiratory distress syndrome in preterm infants, and also to reduce neonatal mortality and morbidity.
However, a recent study of betamethasone in pregnant baboons showed an increase in fetal blood pressure.
But fetal heart rate, maternal blood pressure, and heart rate remain unaffected.
Other studies on fetal sheep also reported the same.
It still needs more studies to test the mechanisms involved and the long-term effects on fetal primates.
Other side effects of celestamine are
- Abnormal hair growth in the body (hypertrichosis)
- Skin burning and itching
- Adrenal suppression
- Skin dryness, redness, and swelling
- Blurred vision or blindness
- Increased sweating
- Menstrual irregularities in some women
- Drowsy and sedation
- Muscle weakness (malaise)
- Circulatory problems
- Heart failure
- Changes in skin colour
- The vulnerability of infectious diseases
- Face Edema
- Enlarged heart and liver
- Rashes around the mouth
- Slow growth and weight gain.
- Shiny skin
- Hypoglycemia and leukocytosis in newborns, and many other side effects.
Before taking the medication, you should first explain to your doctor about your previous and present health condition.
He should be duly informed if you are allergic to betamethasone or other steroid drugs.
Inform him as well if you have any of the following complications
- High blood pressure
- Stomach ulcer
- Kidney and liver problems
- Poor immune system
- Patients with bacteria, fungi and virus infections should avoid the drug as it may suppress your immune response to foreign bodies, making the condition harder.
- Medication should not be given to pregnant and nursing mothers, unless in a special case
- Treatment should not be prolonged as it may cause complications.
Celestamine interactions with other drugs
Before your doctor prescribes the drug for you, he might have known most of the drugs that interact with it.
Just follow his direction and miss none of your doses. Here are some drugs that interact with Celestone
- Anti-diabetic drugs
- Anti-tubercular drugs
- Oral anticoagulants
- Nonsteroidal anti-inflammatory substances
- Estrogen and others.
Frequently asked questions by patients
1. What is celestamine syrup used for?
It is used to control many diseases including allergic conditions, dermatological problems, gastrointestinal diseases, endocrine diseases, haematological disorders, neoplastic disorders, nerves, and many others
What is the celestamine generic name
The generic name for celestamine is betamethasone/Dexchlorpheniramine maleate
2. Is celestamine syrup safe for babies?
No, it is a powerful drug that should not be given to children unless in a special case and is prescribed by your physician.
3. What is celestamine syrup dosage for a 3-year-old child?
The normal dosage for a 3-year-old child is 1/4 tablet or 1/2 tablespoon and is taken 3 times daily. However, your physician will recommend a dose for you based on your health condition.
4. What happens if I take an overdose of celestamine pills
A single overdose of pills may not cause serious symptoms unless at a very high dosage. However, continuous abuse of the drug may cause some side effects like convulsion, insomnia, apnea, heart failure diminished mental alertness, incoordination, drowsiness, etc.
5. Is celestamine good during pregnancy?
Betamethasone is widely used on pregnant women during antenatal to prevent neonatal respiratory distress syndrome in preterm infants, and also to reduce neonatal mortality and morbidity.
Fetus exposure to excess glucocorticoids is suspected to be the fetus origin of the adult disease hypothesis, including heart disease, at 30 years.
However, studies carried out on 534 individuals whose mother received 2 doses of betamethasone stated otherwise.
The study linked the use of betamethasone during antenatal to a greater risk of insulin resistance in adult offspring but had no effect on heart disease for 30 years. It thus recommends the use of a single course of antenatal betamethasone to prevent neonatal respiratory distress syndrome.
Celestone contains both corticosteroid and antihistamine elements. However, it is the steroid that is active in it.
7. Can I use celestamine for cough treatment?
Celestone is not a cough medicine however, it is used with cough drug to reduce the inflammation of an upper respiratory infection, and must be based on a recommendation by your doctor.
8. How long does celestamine take to work?
When taken by injection or oral, the anti-inflammatory effect begins in around 2 hours and lasts for about 7 days.
Is celestamine good during breastfeeding?
Many pregnant and breastfeeding mothers suffer from allergies and are questioning the safety of antihistamine during that vital period.
However, studies have reassured the safety of both the first and the second-generation antihistamines like Cetirizine during breastfeeding since only a small amount that cannot harm the baby is excreted into the milk.
9. Is celestamine bad?
Celestone is not bad. It is a useful drug used in the control and treatment of several conditions, however, its use should be based on doctors’ recommendations to avoid possible side effects.
Does celestamine cause weight gain?
Yes, betamethasone injection comes with some side effects such as weight gain and an increase in blood sugar levels.
Storage and other information
- Keep the drug out of the reach of children. Store it at room temperature (1 to 30 degrees C) and away from light and moisture.
- Discard the unused remainders and do not store them.
Celestone is a powerful steroid medication with both an anti-inflammatory and antihistamine properties, on no account shall you use it without the recommendation and proper dosage from your health care officer.
Don’t fail to inform your doctor if you are allergic to betamethasone or if you have a serious health condition.